Search results for "manufacturing"
Article
N-Glycan Analysis of Biotherapeutic Proteins
Advances in glycoanalysis and glycoengineering will be key to informing research, development, and manufacturing decisions. With glycan research progressing at an accelerated pace over the past two de…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
Scalable and cost-efficient production technologies are needed to enable manufacturing of safe and efficacious clinical-grade virus. Anchorage-dependent cells cultured in roller bottles or cell factor…
Poster
Case Study: Improve Process Economy by Cycling of Prepacked Chromatography Columns
As projects are scaling up to manufacturing scale, it becomes attractive to cycle equipment for specific campaigns for full capture of process economy gains. This customer case study evaluates proce…
Article
The Extreme Costs of a Bioburden Incident
The cost of bioburden incidents can vastly outweigh the costs of preventing them. Read the bioburden article series.
Poster
Resin selection to optimize the flexural strength of bioprocess film
Single-use bioprocess technology offers several advantages for manufacturing biopharmaceuticals, such as increased transportability of fluids throughout the bioprocess workflow and a greater diversi…
Article
Sources of Bioburden You Might Have Missed
A problem with traditional mAb manufacturing is that there are so many potential entry points for microbial contamination. There are, however, ways to shut the door on contamination.
The risk …
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
Resin structures and chemistry will continue to evolve, and many advancements have been made in the past decade that have made the use of mechanistic modeling for achieving efficient manufacturing pos…
Article
HTPD: Optimizing a mAb Chromatography Polishing Step
In addition, steadily increasing demands from regulatory authorities for better understanding and control of manufacturing processes put even more pressure on development work. High-throughput process…
Article
Accelerated flavivirus vaccine production with modern tools and solutions
For downstream processing, modern chromatography resins offer high selectivity and excellent pressure-flow properties for high productivity inmanufacturing-scale purifications. This white paper includ…
Article
Single-Use Extractables and Leachables: Cytiva's Alignment with the BPOG Protocol
For end users who are adopting single-use (SU) equipment as a manufacturing strategy, this situation becomes unwieldy. The need for a standard approach both to the generation and to the reporting stru…