Search results for " assays" in Articles / App Notes
Article
Ligand-Binding Assays and the Determination of Biosimilarity
Consequently, functional assays, such as ligand-binding assays (LBAs) and mechanism of action (MOA) cell-based assays (CBAs), must be developed to effectively assess biosimilars. In many cases, LBAs a…
Article
Make the Switch from ELISA to Biacore™ SPR-Based Assays Today
General guidance on how to convert an existing ELISA assay to a Biacore surface plasmon resonance (SPR) assay and how, by doing so, you can get results in less than half the time compared with ELISA. …
Article
Webcast: Repeatable, automated SPR titer assay for adeno- and adeno-associated viruses in crude samples
Current assays lack the sensitivity required and might be affected by the sample matrix. Fredrik Sundberg at Cytiva shares our recent SPR assay developments for measuring adenovirus and adeno-associat…
Article
Challenging Host Cell Protein Assays for Improved Risk Mitigation
We will address how to challenge your assays early to ensure accurate measurements, build confidence, and reduce the risk of unexpected HCP levels.
Article
Why, Why, Why…ELISA? A Look at the Benchmark HCP Assay
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Biologics developers and manufacturers demand an accurate and reliable assay for host cell protein (HCP) quantitation. Let’s take a close look at why analytica…
Article
Emerging Therapies Test Existing Bioanalytical Methods
It is important to understand the complex assays needed for these programs and work with partners that provide expertise to ultimately expedite these highly complex therapeutic classes.
Specialty …
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
SPR analysis is focused on ligand binding
Ligand-binding assays are key for characterization of biotherapeutic medicines. SPR and ELISA are extensively used in ligand-binding assays. SPR analysis ha…
Article
Using Quality by Design to Develop Robust Chromatographic Methods
Quality-by-design principles can be used to understand chromatographic measurement system variability.
Sep 2, 2014
By: Melissa Hanna-Brown, Kimber Barnett, Brent Harrington, Tim Graul, Jim…
Article
The Importance of Partnering for Bioanalytical Studies
…ho have expertise and in-depth experience in developing and conducting the appropriate bioanalytical assays for a project as well as experience interacting with regulatory authorities.
BioPharm…
Article
Host-Cell Protein Measurement and Control
…ently required that HCP be routinely monitored at the purified bulk level, using suitable analytical assays. Results from batch to batch should be consistent and meet specification limits” (8).
R…