Search results for " Elisa" in Articles / App Notes
Article
Introducing the VH3 ligand ELISA kit
Our new VH3 ligand ELISA kit - the latest addition to Cytiva’s impurity portfolio - is the only commercial solution dedicated to testing VH3 ligand leakage. This kit is essential for users of MabSelec…
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Make the Switch from ELISA to Biacore™ SPR-Based Assays Today
General guidance on how to convert an existing ELISA assay to a Biacore surface plasmon resonance (SPR) assay and how, by doing so, you can get results in less than half the time compared with ELISA. …
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Impurity ELISA automation for faster process development
This blog highlights how Cytiva impurity ELISA kits are easily integrated into automated systems such as the Biomek i5 to increase throughput, while maintaining the same robust and sensitive results y…
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Host cell protein quantitation using ELISA
This application note shows how using the sensitive HCPQuant™ CHO ELISA kit (Cytiva) and automating wash steps using Aquamax 4000 Microplater Washer (Molecular Devices) enables fast results without co…
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Why, Why, Why…ELISA? A Look at the Benchmark HCP Assay
Let’s take a close look at why analytical scientists turn to the ELISA and how it fits into process development.
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News: Cytiva Adds ELISA Kit to End-to-End HCP Monitoring Capabilities
Cytiva is pleased to announce the new Amersham HCPQuant CHO kit, a generic for detecting host cell protein impurities in drug samples produced in CHO cell lines.
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Host-Cell Protein Measurement and Control
Using these polyclonal antibodies, a multi-analyte sandwich ELISA can be developed (see Figure 1). In Figure 1, capture antibodies enrich the HCPs from sample and immobilize them to a 96 (or greater)-…
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Emerging Therapies Test Existing Bioanalytical Methods
…ese characteristics are often not traditional liquid chromatography–mass spectrometry (LC–MS) or ELISA used to quantify small- and large-molecule therapeutics and biomarkers. The May 2018 FDA Bioanal…
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Impurity Testing of Biologic Drug Products
Process-related impurities and residuals such as Protein A can be detected and quantified with ELISA assays, whereas host cell residual DNA can be quantified via quantitative polymerase chain reaction…
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Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
SPR and ELISA are extensively used in ligand-binding assays. SPR analysis has been used for antibody characterization for more than 20 years. The sample readout from an SPR system such as Biacore (Cyt…