Search results for " analysis" in Articles / App Notes
Article
Use of Multivariate Data Analysis in Bioprocessing
Multivariate data analysis (MVDA) has emerged as a significant enabler in this regard (3-5).
A thorough search on use of MVDA reveals its applicability in fields as diverse as polymers, semiconduc…
Article
N-Glycan Analysis of Biotherapeutic Proteins
What’s in a (glycan) name?
To inexperienced researchers, an initially intractable idiosyncrasy of N-glycan analysis is the number of N-glycan nomenclatures in current use. This can complicate inte…
Article
Analysis of Glycosylation in Biosimilars
Determining glycosylation patterns
Glycosylation pattern analysis is a step-wise process. As a simple first step, it may be enough to assess the type and amount of each monosaccharide composing th…
Article
Methods Accelerate Biosimilar Analysis
Focus is placed mainly on high-resolution mass spectrometry (HR-MS) for primary structural analysis and characterization of post-translational modifications and various biophysical techniques for high…
Article
Protein Analysis with Size Exclusion Chromatography
This white paper presents fundamentals about analytical SEC and describes how our new-generation agarose-based SEC columns are used in analysis of biomolecules.
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Article
Ensure SEC Column Reproducibility in Protein Drug Analysis
Size exclusion chromatography (SEC) is the go-to analytical method in the analysis of therapeutic protein drugs. This article describes the factors affecting the reproducibility of columns and how you…
Article
Using Multiple Techniques in Biosimilar Analysis
Case study: preliminary peptide analysis
In this example, a medium-sized peptide was investigated. This system presented challenges due to the small size and limited structure of the peptide. Two o…
Article
Analysis of mRNA Therapeutics and Vaccines
Analytical approaches must keep pace to ensure the identity, safety, and efficacy of evolving mRNA candidates.
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Article
HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
If used correctly, these methods can reduce analysis and development time and thus accelerate the progress of therapeutic proteins toward the clinic.
REGULATORY EXPECTATIONS FOR THE ANALYSIS OF MA…
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
Therefore, NIR does not provide specific identity of the studied material and requires a use of spectral libraries or multivariate data analysis (MVDA) for spectra evaluation. NIR spectroscopy is a ve…