Search results for " lab-scale"
Article
How to Pack Lab-Scale Columns
See below for resources and tips for how to usefully pack lab-scale columns.
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Article
How to Pack Lab-Scale Columns
Watch how-to videos >>
Learn how to pack Tricorn™ and XK chromatography columns. Our new video tutorials show step-by-step instructions for a well-packed column.
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Using Digital Twins to Model Process Chromatography
Models are typically calibrated using lab-scale data for material and cost efficiency, with the model then scaled to predict manufacturing scale by accounting and simulating changes to scale, operatio…
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Connected, Automated Downstream Process for mAb Screening and Evaluation
This study was done to show both proof of principle for an automation solution for a lab-scale protein purification set-up, and that it would significantly decrease hands-on time, while assuring that …
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Your Protein Purification Questions Discussed
In one of Cytiva´s web chats, ÄKTA™ system users asked questions relating to lab-scale protein purification and ÄKTA systems, which experts answered during a live session.
The expert…
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Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Figure 3: Selectivity between monoclonal antibody (mAb) monomers and aggregates at a higher sample load following the optimized first polishing step in a lab-scale column, showing the percentage of fr…
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Enhancing Resins Addresses Purification Concerns
In lab-scale processing, lithium chloride precipitation may work well, but scalability of such a process is poor, Deorkar states. Affinity chromatography, such as oligodT is commonly used for a captur…
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Process Development: 2020 Reflections and 2021 Possibilities
More Popular Articles of 2020
The following are some of the year’s best articles from Bioprocess Development Forum:
Purification of Plasmid DNA
How to Pack Lab-Scale Columns
Gene The…
Poster
Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
…d scalable technology: a 50-fold scale-up of a three-column PCC (3C PCC) mAb capture step within the lab-scale ÄKTA™ pcc system and a 294-fold scale-up directly from lab to manufacturing scale. …
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Protein Purification Questions and Answers from ÄKTA Club Web Chat
Web chats, where Cytiva experts answer questions about protein purification and ÄKTA lab-scale systems during a live session, are recurring events within ÄKTA club.
Questions and answers…