Search results for " report" in Articles / App Notes
Article
Industry Adoption of Single-Use Systems Remains Low
…he portion of single-use technologies is already between 25% and 50%, and the market growth has been reported to be around 20% in the past three years,” adds Parrish Galliher, chief technology office…
Article
3rd BioProcessing Asia Preview: Q&A with John Curling
Given approvals of gene and cell therapy treatments in 2016-2017 and recent reports of positive clinical trial outcomes for the AAV-FVIII gene therapy treatment of Hemophilia A, I believe that develop…
Article
Transformative Medicines Challenge FDA and Manufacturers
FDA reports that some 40 companies are developing CAR-T technologies for multiple indications and that it is monitoring more than 600 active investigational new drug applications (INDs) related to gen…
Article
ADC Development Robust Despite Lackluster Performance
Roche, “Annual Report 2016 [4],” accessed Oct. 20, 2017.
4. SEC, “Seattle Genetics Form 10-K [5],” accessed Oct. 20, 2017.
5. Seattle Genetics, “Strong Development Pipeline [6],” accessed …
Article
Development of Purification for Challenging Fc-Fusion Proteins
This phenomenon is interesting and has been reported as the “reverse salt effect” (12).
Figure 3. Yield and high molecular weight impurities reduction profiles at varying counterion conce…
Article
Avoiding Investigational Failures and Discrepancies
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Reduces duplicated efforts and data entry errors
Simplified tracking, trending, and report creation
Optimized quality processes and streamlined implementation of preventive…
Article
Best Practices for Data Integrity
BioPharm: How can manipulation of electronic records be detected and prevented?
Painell (IDBS): The use of audit logs that cover all data entry, calculations, and reporting will help prev…
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Improvements in Protein A Chromatography
Recently people have reported in excess of 500 cycles on protein A. While this provides great value for routine manufacturing of large quantities of mAb, the value should be balanced against the devel…
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Witnessing Major Growth in Next-Generation Antibodies
De Fougerolles expects Ablynx to report results of an on-going Phase III study in the second half of 2017 and be at the approval stage in 2018.
“There are very few limitations when it comes to the…
Article
Downstream Processing for Cell-Based Therapies
Addressing the DSP challenges
Table I: Overview of ultra scale-down tools reported in literature as predictive tools for several different large-scale downstream processing steps and/or processing…