Search results for "bioreactors"
Article
Paring Down Impurities in Downstream Processing
Bioreactors to house these systems might be stirred-tank, air-lift, fixed-bed, hollow-fiber perfusion, or suspension, perhaps even hybrid combinations thereof. All of these lead to a gamut of membrane…
Article
Report from the 6th International HTPD Conference
…ividual cells on the plate has evolved, along with case studies on microwell-based pseudo perfusion bioreactors. The presentation concluded with an outlook of future research areas which included int…
Article
Digitalization: The Route to Biopharma 4.0
Semi-Continuous Scale-Down Models for Clone and Operating Parameter Screening in Perfusion Bioreactors. Biotechnol Prog. 2019, 35 (3), e2790. DOI: 10.1002/btpr.2790.
5. Wolf, M.; Bielser, J. M.;…
Article
rAAV Production Using HEK293 Cell Line and Transfection Medium
Improving the performance of a scalable AAV process in Xcellerex™ XDR-10 and XDR-200 bioreactor using HyClone™ peak expression medium.
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Article
Designing a 1.5 L Bench-Scale Model of a Perfusion Process
Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discus…
Webcast
Find the Right Intensification Strategy for Your Upstream and Downstream Processes
How do you know if an intensification approach will give you advantages over your current biomanufacturing process, and how do you choose the right one? Learn more from our process intensification exp…
Article
An open bioprocess innovation challenge!
…nd the related bioprocess!
Learn more about 2022 participants and AI web-based virtual bioreactors, innovative sensor systems, surface that purifies biomolecules by electronic signals, a…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
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As process intensification is adopted into large-scale manufacturing, the responsibility on scale-down models to accurately represent the expanded operating space quickly follow…
Article
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
Article
Webcast on Demand: Find the Right Intensification Strategy for Your Upstream and Downstream Processes
How do you know if an intensification approach will give you advantages over your current biomanufacturing process, and how do you choose the right one? Learn more from our process intens…