Search results for " scaling"
Article
Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
This article highlights 15 years of changes in biopharmaceutical manufacturing.
By Ronald A. Rader, Eric La…
Article
Understanding Validation and Technical Transfer, Part 3
Understanding Validation and Technical Transfer, Part 3
Validation ensures safe and effective biologic products that benefit the patients whose health and wellbeing depend on the therapies. Part 1 |…
Article
Putting Viral Clearance Capabilities to the Test
Process understanding and careful assessment of risks are essential in developing viral clearance programs.
By Rita C. Peters
nobeastsofierce/Shutterstock.com
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Article
Going Viral
How a new factory-in-a-box is helping scale up manufacturing of viral vector-based therapies to reach more patients.
Manufacturing viral vector-based therapies such as vaccines and gene…
Article
Industry Adoption of Single-Use Systems Remains Low
Single-use technologies are starting to gain ground as capacity needs change, but industrywide adoption remains low.
By Feliza Mirasol
zli…
Article
Driving Change in Biomanufacturing
The large buffer volumes required for biomanufacturing can be a bottleneck, especially when scaling up. Just-in-time buffer preparation can be the solution. In this blog, we discuss the two most commo…
Article
Development of Purification for Challenging Fc-Fusion Proteins
Development of Purification for Challenging Fc-Fusion Proteins
This study outlines methods for an alternative protein-polishing process for challenging proteins.
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Poster
Case Study: Improve Process Economy by Cycling of Prepacked Chromatography Columns
As projects are scaling up to manufacturing scale, it becomes attractive to cycle equipment for specific campaigns for full capture of process economy gains. This customer case study evaluates proce…
Poster
Fast Trak Services: a collaborative project to accelerate downstream biosimilar process development
Biosimilars represent an innovative solution that can benefit both patients and healthcare systems by reducing the burden of rising treatment costs. To improve the availability, price and access of…
Article
Evaluating E&L Studies for Single-Use Systems
Critical aspects and lessons learned
The third option revealed the following considerations:
• The scaling down of the system had to be representative of the actual process and simul…