Search results for " efficiency" in Articles / App Notes
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A deep dive into optimizing AAV capture and polishing to maximize both yield and purity
As demand for AAV vectors grows, so does the need for scalable and cost-efficient purification processes. It’s critical to maximize both overall yield and removal of impurities, including empt…
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Getting your investigational drug regulatory ready
Navigating regulatory requirements can be an overwhelming and time-consuming part of the translational journey. From the submission of an investigational new drug (IND) application, regulators…
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As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Development beyond traditional monoclonal antibodies (mAbs) is increasing, and today, we see antibody variants like multispecific and bispecific antibodies and antibody fragments. In mAb proc…
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Innovations in Downstream Processing
Innovations in downstream processing accelerate development, enhance efficiency, and promote sustainability.
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HTPD 2023 conference is coming up. What will be discussed and what happened last time?
The 6th international conference devoted to high-throughput process development (HTPD) and smart process development (PD) will take place on October 31 – November 2 in Valletta, Malta.
A…
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Determining and Optimizing Dynamic Binding Capacity
Dynamic binding capacity (DBC) indicates the quantity of a specific biomolecule that can be bound during a chromatography purification step under a specific set of process conditions. Determ…
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How to develop a scalable rAAV process
Adeno-associated virus (AAV) is the most common vector for gene therapy, yet there’s much room to improve production, purification, and analytics. Here we present the latest updates to our wor…
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On-demand: ÄKTA process™ system virtual demo
Improving usability, efficiency, and reliability were our focus when we designed the new ÄKTA process™ system.
In this virtual workshop Torbjörn Blank will explain how the ÄKTA pr…
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Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
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Modern plasmid purification process
AcuraBio selects Cytiva's latest two-step purification protocol to offer a productive plasmid DNA service to its customers globally to alleviate supply constraints for mRNA and cell & gene th…