Search results for " efficiency" in Articles / App Notes
Article
Biotechnology Innovation and Growth in Israel
According to global data compiled by Bloomberg, Israel ranked fourth in healthcare efficiency (1). This ranking is particularly impressive considering the relatively moderate level of resources alloca…
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Trends in Downstream Bioprocessing
With CMO profits dependent on their efficiency and dealing with many more products and with clients paying the costs for CMO implementation of new technologies, CMOs apparently implement novel downstr…
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State of Quality and Compliance in the Biopharmaceutical Industry
Use technology efficiently
Technology should introduce simplicity and efficiency, not complexity and inefficiency. Great technologies can become great impediments quickly. Unfortunately, there is …
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A Platform Approach for the Purification of Domain Antibodies (Dabs)
This platform approach, based on a capture step with Capto L, enables increased efficiency and productivity in developing therapeutics based on Dabs.
Click here to download the application not…
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The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
This application note describes the performance of single-use Xcellerex XDM Quad Mixing System used as a slurry tank when packing chromatography columns. The capability of the mixing system to keep …
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Evaluating the Use of Continuous Chromatography
But to increase efficiency and promote flexibility, biomanufacturers are looking to implement continuous downstream process development. However, despite successful laboratory trials, it has remained …
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
…as working together helps facilitate the introduction of new solutions that can dramatically improve efficiency, productivity, quality, and safety.
Sterile filtration will remain the standard, but…
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Purification strategies for antibody-derived entities: bispecifics and fragments
The safety and efficiency requirement of conventional mAb processes are key also for antibody variants. Here we present strategies for purifying bispecific antibodies and antibody fragments having the…
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Alternative solutions to separate AAV full and empty capsids using anion exchange
Adeno-associated virus (AAV) is the main vector for gene therapy and there is need for scalable, cost-efficient, and robust chromatography-based purification. Key for a successful process are …
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A scalable single-use two-step plasmid purification process
The current global demand for biopharmaceuticals is over USD 300 billion, with an estimated growth of ≥ 12% annually. While MAb processes have become much more efficient, production of mRN…