Search results for " variability" in Articles / App Notes
Article
Chromatography innovations for the diversified antibody pipeline
Introducing MabSelect™ VH3 affinity resin for antibody variants
At Cytiva, we connect with process developers and manufacturers to understand their needs and strive to make t…
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Digitalization: The Route to Biopharma 4.0
Industry 4.0, also known as the Fourth Industrial Revolution (4IR), will result in the digital transformation of the manufacturing sector. It is propelled by transformative trends such as the prolif…
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As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Development beyond traditional monoclonal antibodies (mAbs) is increasing, and today, we see antibody variants like multispecific and bispecific antibodies and antibody fragments. In mAb proc…
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Determining and Optimizing Dynamic Binding Capacity
Dynamic binding capacity (DBC) indicates the quantity of a specific biomolecule that can be bound during a chromatography purification step under a specific set of process conditions. Determ…
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Report from the 12th Plasma Product Biotechnology Forum
The general trend was considered more interesting than specific values predicted, as scale-up and variability of analytical methods were not considered.
Another aspect of technical development …
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Top Process Development Trends for 2021 and a Look into 2022
It focuses on the evaluation of intra- and inter-batch variability and can be applied to both large- and small-molecule pharmaceuticals.
Bioprocess Development Forum readers also focused on efficie…
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Making Your Bioprocesses More Efficient
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Bioprocess intensification lets you maximize productivity while minimizing one or more key variables of your current biomanufacturing proces…
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Process Development: 2020 Reflections and 2021 Possibilities
Another prominent topic of the year was process variability, which can significantly impact biomanufacturing outcomes and is influenced by various factors, including variations in process parameters o…
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Faster, Smaller, Cheaper: Optimize Your Bioprocess Facility
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Bioprocess intensification lets you maximize productivity while minimizing one or more key variables of your current biomanufacturing process, such as time, volume, or…
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Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…