Search results for " process" in Articles / App Notes
Article
Taking Prepacked Columns to Manufacturing Scale
Prepacked chromatography columns in biomanufacturing can save time, but also present concerns related to delivery lead times, capacity, and operational cost.
Learn more here about ways to address…
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Tools and Solutions for Separation of Charged mAb Variants
Biomolecules, however, exhibit high structural complexity and are often sensitive to alterations in the manufacturing process.
This work aims to demonstrate different strategies to alter the dist…
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Driving Change in Biomanufacturing
Whatever the objective, driving change is a challenge. Implementing a new technology into a bioprocess is a big change. The new technology must be fully understood, all regulatory requirements fulfi…
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Prepare for an FDA Bioburden Inspection
A best-practices response will not only help you be prepared for any upcoming FDA inspection, it may also yield valuable insights to help improve processes and procedures. Anastasia Lolas, former FDA …
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Patenting Prospects for Cell-Based Therapies
… codified as Section 101 of the Patent Act:
“Whoever invents or discovers any new and useful process, machine, manufacture, or composition of matter, or any new and useful improvement thereof, …
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Tips for Protein Purification Method Editing
Protein purification questions and answers from ÄKTA club web chat.
Find out how to quickly generate tailored automation methods in your UNICORN™ software in this blog.
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Sources of Bioburden You Might Have Missed
The risk is most acute in the upstream process, which should not be a surprise. What better place for a bacterial contamination to grow than in a well-aerated, nutrient-loaded cell culture medium? Dow…
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Efficient concentration of a low-titer bovine IgG with high recovery in low volume
The described process enabled concentration of a bovine IgG antibody from 50.0 to 0.165 L in less than 5 h.
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Increase Efficiency in Experimentation with Design of Experiments
Also, good planning and relevant experiments are making the data evaluation more rigid, so that the outcome is not only generated by chance, but will result in more robust processes and predictable ou…
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Walk Away and Do More Screening Preps
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified protein, and substantial hands-on time might be allocated to…