Search results for " downstream"
Article
How to Use Multiwell Plates With Manual Operation
During process development, aspects like robustness, scalability, and GMP production come into play. FDA initiatives such as quality by design (QbD) put demands on better process understan…
Article
Current Trends in Host Cell Protein Detection for Biologics Manufacturing
Commonly accepted HCP analytical methods, the challenges of HCP assay, and recommendations on what can easily be accomplished in-house and when it may be better to outsource.
Read more here…
Article
See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
Article
Top Process Development Trends for 2022 and a Look into 2023
Mainstream articles, no pun intended, covering tools and methodologies for smarter downstream process development were highly popular. Smart process development being a collection of approaches to imp…
Article
mRNA: The Messenger - mRNA Synthesis
… optimizing the mRNA template design, in vitro transcription, and process parameters to simplify the downstream processing.
EXPLORE THE mRNA UNIVERSE HERE >>
Article
Capture of Bispecific Antibodies and Removal of Product-Related Impurities
The similarities between these impurities present extra challenges for downstream processes, especially post-capture. One potential solution is to initiate polishing at the capture step using differen…
Article
Developing a Robust Bioprocess Using Mechanistic Models
The safety and efficacy of a biopharmaceutical drug are of the highest priority. Therefore, manufacturers have to design, implement and maintain measures to ensure that the bioprocess con…
Webcast
Recovery of Biological Products XIX
The agenda will include progress on the state-of-the-art technologies and emerging trends in downstream unit operations for diverse biotherapeutic modalities (e.g. proteins, peptides, cell and gene …
Webcast
Biotech Makers: Tools and top tips for faster process development
Listen to speakers from Byondis and Cytiva in our first 'Biotech Makers Workshops' event on the 30th March (2pm CET).
We will discuss top tips and tools for faster process development to help you a…
Webcast
Conference: Chromatography modeling days
If you’re a process developer, modeler, or innovator in the biopharma downstream community, you are invited to share and discuss success stories, best practices, and current challenges and pain poin…