Search results for " downstream"
Article
Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
…cosylation pattern, then folks are going to say, “I can't clean this up with chromatography in the downstream step. We have to go back to the beginning, get better control over the process.”
Ag…
Article
In silico Approaches towards Automated Biomanufacturing
The goal of manufacturing is to control and maintain a commercial process capable of consistently producing a drug of the highest quality and safety. As part of manufacturing science and t…
Webcast
Improving the Oligonucleotide Synthesis Experience
We often hear from scientists working with oligonucleotide synthesis that the technical complexity of the process can be a roadblock for some users. Addressing this challenge was one of Cytiva’s main …
Article
The GMP of AAV: Purification for Clinical Production
Watch this presentation to learn about the key considerations when developing a purification process for adeno-associated viruses (AAV).
>>> Learn more
Article
Track-and-Trace Progress Benefits Supply-Chain Security Efforts
By Agnes Shanley
The industry has made great strides in implementing serialization technologies, while technology developers are enabling more open access to real-time transportation data.
S…
Article
Antibody Production Workflow
Explore the workflow here >>
Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific antibodies, antibody fragments, antibody-drug conjugates (ADCs), and m…
Webcast
Strategies and emerging technologies for mAb capture
You will learn:
• Strategies and emerging technologies for intensifying the mAb capture step
• How the design of your upstream mode may determine your optimal downstream solution
• When techn…
Article
Assessing Manufacturing Process Robustness
This will include, but will not be limited to, materials, upstream and downstream process parameters, equipment parameters, hold times, operational variables, operation/analytical personnel, instrumen…
Article
Cytiva Acquires GoSilico and Strengthens Digital Capabilities in Bioprocessing
The scientific software maker GoSilico creates “digital twins” of downstream processes, a method that is increasingly used to enhance process development by simulation. Mechanistic modelling saves tim…
Article
Virtual Scientific Symposium: Process Development: Go Smarter, Go Faster!
View the agenda and register to attend here.
In this free virtual symposium, you'll hear from leaders at GlaxoSmithKline, Byondis, UCB, UCL, GoSilico, and Cytiva on how they balance innovati…