Search results for " titer"
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
Similar virus titers and HA concentrations were measured in the 10 L culture (data not shown) as in the 50 L culture (Fig 4).
A more detailed description of the cell culturing and virus infecti…
Webcast
Webinar: Building an Innovative Integrated Continuous Downstream Manufacturing Platform for the Production of Biologics
It involves dealing with variable perfusion flow rate, normalization of dynamic perfusion titer profile, sizing between intermittent (bind-elute chromatography) and continuous (viral inactivation) uni…
Article
A Closer Look at Affinity Ligands
Affinity ligands play an exciting role in the ever-growing sphere of downstream processing. In speaking with BioPharm International®, Phillip Elliott, PhD, associate director of Process Development,…
Article
Dear lentivirus: We have not forgotten about you and how to improve your polishing recovery
To maximize physical and infectious titer, it’s important to carefully tune the conditions of each downstream step with these sensitivities in mind.
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Article
Enhancing Resins Addresses Purification Concerns
“As upstream processing continues to increase titers of these biologic molecules, improving on current chromatography resins to increase the dynamic binding capacity while enhancing separation to remo…
Article
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
coli growth measured as optical density at 600 nm (OD600), plasmid titer, and percentage of produced supercoiled (SC) plasmid DNA was comparable at all culture volumes tested.
Explore th…
Article
Setting Up Bioprocessing Systems for Digital Transformation
Predicting equipment failures, intensifying bioreactor titer, and improving facility throughput capacity are all examples of companies looking at all or parts of a biopharmaceutical manufacturing proc…
Article
Process Development: Go Smarter, Go Faster! Available on Demand
…ment with the latest techniques and ways of working
• Enhance outcomes: Increase titers and yields while ensuring robust processes
• Overcome obstacles: Address the challenges generated …
Article
HyClone Characterized FBS – Origin Equivalence Study
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Fetal bovine serum (FBS) is still used in many cell culture applications, including viral vector production. FBS from a single origin may be limited, so qualifying FBS from …
Article
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