Search results for "scale up" in Articles / App Notes
Article
New Therapies Present Scaling Challenges
Bioreactor size can be increased (scale up), or the number of bioreactors used can be increased (scale out). In addition, mammalian cell culture technology has advanced such that producing multi-kilog…
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Scaling Up Novel Therapies
Bioreactor scale-up
In more traditional biopharmaceutical development, bioreactors are typically the most difficult pieces of equipment to scale up, says Fredrik Lundström, product manager for…
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Current Techniques and Challenges Presented in Scaling Between Bioreactors
cell culture
In this video, Andreas Castan, Strategic Technology Partnerships Leader at Cytiva, discusses the current techniques and challenges in scaling between bioreactors.
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Going Small to Achieve Success on the Commercial Scale
Scale-down modeling is instrumental in supporting the development of downstream biopharma manufacturing processes.
By Cynthia A. Challener
Biopharmaceutical manufacturing involves a series o…
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Simplify-bioreactor scale up and scale down: applications and tools
Scaling the physical environment in a bioreactor is a frequent task in each product development project. A well-designed scaling strategy, workflows, and easy-to-use tools will facil…
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Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
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Improving Productivity During Process Development and Scaling of Your Process
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Andreas Castan, PhD, Strategic Technology Partnerships Leader of Business Development & Strategy at Cytiva, provides helpful insig…
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Interactive eBook - Understand and unlock the potential of digital scaling
Ready for smarter scaling? Explore the possibilities with a digital process to reduce time and costs associated with your operations. Get started by downloading our free eBook.
DOWNLOAD EBO…
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Challenges of scaling up buffer production for GMP and how to evaluate different solutions
This virtual workshop presents different options for scaling up buffer production. You will learn at what scale does it make sense to outsource your buffer production or invest in a hardw…
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Approaches to scaling up Chromatography Processes
Scaling up chromatography resins requires a thorough understanding of their intended use.
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