Search results for " pure" in Articles / App Notes
Article
A Look at the Affinity Chromatography Landscape
…tes along with high binding capacity and productivity, resulting in a final sc pDNA product suitably pure for therapeutic applications,” he explains.
Cytiva has increased the window of operati…
Article
Increase Throughput with Automation in Multistep Purification
When there is simply not enough time to purify proteins needed or when everyone has too much to do, automation can be the answer for multistep protein purification. See how a biotech startup uses auto…
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Your Source of Information for Automated Multistep Protein Purification
Increasing the level of automation in protein purification can free up time and allow other tasks to be performed while the chromatography system is working. Cytiva has gathered recourses to support a…
Article
Impurity Testing of Biologic Drug Products
Experts share insights on the various methods used for purity and impurity analysis of therapeutic proteins.
By Adeline Siew, PhD
CA-SSIS/shutterstock.comIm…
Article
Reliability Rooms and the Move to Proactive Supply Chain Management
Grounded in pure, fundamental data analytics, this concept is roughly translated as “gathering all the information that is required to make fast, sound decisions that enable robust and sustainable imp…
Article
Development of Purification for Challenging Fc-Fusion Proteins
All chromatography runs were performed using a Cytiva ÄKTA Explorer or Pure system installed with Unicorn software version 6. HIC and CEX columns were packed in a vantage 0.66-cm or above column …
Article
Patenting Prospects for Cell-Based Therapies
The invention was directed to methods for producing pure cultures of mature hepatocytes to be used for testing, diagnostic, and treatment purposes. Hepatocytes in the prior art were disadvantageous fo…
Article
Bioburden Control in the Biopharmaceutical Industry
According to the Public Health Service (PHS) Act and as illustrated in Figure 1, the biological product must be safe, pure, and potent.
The basic standards for establishing …
Article
Unifying Continuous Biomanufacturing Operations
The success of a truly integrated continuous processing platform relies on the collaborative efforts of upstream and downstream specialists.
By Randi Hernandez
When human cells travel throug…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
The problem with this method would be obtaining sufficient quantities of pure isolated variants, as some of the variants may be present in a small amount and merge with other variants.
Step 4: M…