Search results for " costs"
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Cycle-time reduction
Single-use technology implementation in chromatography can greatly reduce cycle times, lower operating costs and energy consumption, and generate less waste, according to Young…
Article
Re-use of Protein A Resin: Fouling and Economics
In a typical platform process for production of mAb therapeutics, approximately 80% of the total process costs are for the steps following fermentation, with up to 60% of the downstream costs coming f…
Article
The Bullish Outlook for Biosimilars
Biosimilar markets at different stages
As healthcare costs continue to rise, there is a global imperative to find cost-effective countermeasures. Despite broad recognition that biosimilars may offe…
Article
Reimagining Affordable Biosimilars
While effective and successful, biotherapeutics are presently marred by their high costs, which make their affordability poor for most of the world and thereby limit their accessibility.
The adv…
Article
Technology Innovations Improve Process Chromatography Performance
Reducing the costs for cleaning and cleaning validation are also challenges that many big companies and contract manufacturing organizations (CMO)/contract development and manufacturing organizations …
Article
Monitoring and Control of Inline Dilution Processes
Buffer management has received less attention, despite the high costs and labor-, space-, time-, and material-intensive nature of this common downstream activity. Inline dilution (ILD) combined with i…
Article
A Plastic Pipeline for Commercial Bioprocessing?
Lower capital costs for facilities and equipment, lower operating costs, smaller equipment footprints, lower overhead costs, flexibility of system configurations, faster changeover times, the reductio…
Article
Perfusion in the 21st Century
Now, improved continuous culture technologies such as perfusion are on the rise, as biosimilar manufacturers look for new ways to cut costs while increasing quality and productivity.
With perfusio…
Article
Comparing Protein A Resins for Monoclonal Antibody Purification
A prototype Protein A resin is evaluated for purification performance, reusability, and cost performance.
With greater economic pressure on monoclonal antibody (mAb) production for therapeutic …
Article
Evolution of the Monoclonal Antibody Purification Platform
A recent study has compared ATPS to the currently established platforms in terms of costs and environmental impact (16). The authors reported that the ATPS offers considerable advantages in terms of p…