Search results for "single-use" in Articles / App Notes
Article
Ensuring the Biological Integrity of Raw Materials
Single-use manufacturing devices, disposable consumables, and ready-to-use reagents and media are also reducing rates of contamination in the industry.
Faster, more accurate tests are being introd…
Article
Mixing dynamics in a large volume single use mixer
Large volume single-use technology mixers can be used for mixing operations throughout the entire bioprocess workflow. Large-volume mixers are mainly required in clinical three-scale and production…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
There were also new, related challenges, such as an increased sensitivity of animal-component-free cultures to toxic contaminants, metabolic waste products, or leachables from polymers used in single-…
Article
Process Chromatography Selection for Downstream Processing Applications
Other simplifications are single-use systems where critical systems components (columns, flow kit etc.) are used for one campaign only, omitting the cleaning steps and the need for cleaning validation…
Article
ReadyToProcess™ Prepacked Columns
ReadyToProcess columns are high-performance bioprocessing columns prepacked with a range of bioprocess resin and are supplied ready for use. As a supplier of both the chromatography resin and the pr…
Article
An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
Testing product and process intermediates alone is helpful, but does not provide a complete solution to viral safety. This article proposes integrated solutions for systemic and proactive viral risk m…
Article
Platform Approach Speeds Process Development
Figure 3: Normalized product concentrations (A) and viable cell concentrations (B) of a fed batch process performed at 100-L scale in single-use bioreactors before and after direct process transfer fr…
Article
Continuous Processing for the Production of Biopharmaceuticals
The increased use of multimodal resins and single-use technologies can also play an important role in continuous operation.
Individual efforts made by different researchers to make unit operations…
Article
Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
This application note describes the performance of single-use Xcellerex XDM Quad Mixing System used as a slurry tank when packing chromatography columns. The capability of the mixing system to keep …
Article
Cleaning of Dedicated Equipment: Why Validation is Needed
If they use disposable equipment, such as single-use bioreactors, compatibility of the disposable equipment with the process should also be assessed.
Companies manufacturing only one product use d…