Search results for " cell" in Articles / App Notes
Article
Elucidating Biosimilars Characterization
Biological molecules are also manufactured by processes involving living organisms, such as genetically engineered bacteria, yeast, or mammalian cells, and although these processes can be well-defined…
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Report from the 6th International HTPD Conference
Since then, HTPD in chromatography applications has been well established among most biopharmaceutical companies but has also expanded to upstream and cell culture screening as well as to formulation …
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Digitalization: The Route to Biopharma 4.0
In microbial cell cultures, scale down models such as micro well plates (3) and deep well plates are employed, whereas shake tubes/flasks are widely used in mammalian cultures (4). However, most of th…
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Reimagining Affordable Biosimilars
Cost of biosimilar development
Development of biosimilars begins with cloning the appropriate host cells with the target gene. This is a multistep process involving upstream processes (e.g.,…
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Cytiva Invests $500 Million Over 5 Years to Expand Global Capacity
Further, the company’s locations in Singapore and Pasching, Austria, are increasing output through increased personnel and additional work shifts, following a tenfold increase in powdered cell culture…
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A Diverse Landscape of Patent Issues Seen in the US, UK, and the EU
Gene and cell therapy patent issues
BioPharm: What are the biggest issues that biotech faces surrounding the patenting of gene and cell therapies?
England (Taylor Wessing): Medical science i…
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Getting a Handle on Biopharma’s Most Critical Quality Attributes and Quality Control
Biopharmaceutical manufacturers thus face a huge hurdle in bringing more advanced manufacturing and process control methods to the manufacture of cell and gene therapies. “New approaches will be neede…
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Manufacturing of Viral Vectors
This trait is used by molecular biologists for the delivery of genetic materials into cells. Viral vectors are also explored for use in gene and cell therapy and as the basis for prophylactic and ther…
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The Challenge of Disruptive Technologies in Bioprocessing
Other drivers relate to gaps in process performance, for example, “the notorious weakness of harvesting technologies in the face of the ever-increasing biomass from highly productive mammalian cell cu…
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Modeling and Miniaturization: Key Topics at Successful HTPD Conference
Since then, HTPD in chromatography applications has been well established among most biopharmaceutical companies, but has also expanded to upstream and cell culture screening as well as to formulation…