Search results for " MabSelect" in Articles / App Notes
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
… hetero- and homodimers for bsAb’s, and removal of light chain from mAbs during elution when using MabSelect™ VL protein L resin. The video includes results of these experiments and a discussion of h…
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Re-use of Protein A Resin: Fouling and Economics
Some of the major Protein A resins that are commercially available include MabSelect (Cytiva), MabSelect Xtra (Cytiva), MabSelect SuRe (Cytiva), MabSelectSuRe LX (Cytiva), ProSep Ultra Plus (EMD Milli…
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Process Economy Simulations on a Protein A Capture Step
This application note gives calculation examples that highlight scenarios where the enhanced capacity and alkaline‐stability of MabSelect PrismA can provide process economic benefits to large‐scal…
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Capacity and Performance of a Next Generation Protein A Chromatography Resin
The resin exhibits improved capacity over its predecessor MabSelect SuRe™ products, while maintaining purification performance. This application note demonstrates the binding capacity and purification…
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Chromatography innovations for the diversified antibody pipeline
Our MabSelect™ VH3 affinity resin interacts with the variable heavy chain of the VH3 sequence family of human antibody, delivering high binding capacity and efficient separation of product-related imp…
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As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Cytiva expands the antibody capture resin toolbox and has recently announced MabSelect™ VH3 affinity resin. MabSelect VH3 uses an engineered protein A resin that interacts only with the variable heavy…
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Protein L affinity resin is ready to move to manufacturing
The MabSelect™ VL protein L resin now offers improved alkaline stability compared to Capto™ L resin and a two-fold or more increase in dynamic binding capacity (DBC) in certain applications. After com…
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Comparing Protein A Resins for Monoclonal Antibody Purification
A team from Chugai Pharmaceutical (Japan) investigated the mAb purification performance of a new alkali-tolerant, prototype Protein A resin (Resin 3, MabSelect SuRe LX prototype, Cytiva), which has th…
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Introducing the VH3 ligand ELISA kit
This kit is essential for users of MabSelect™ VH3 resin in process development and production, providing a comprehensive and reliable solution.
Learn more about the VH3 ligand ELISA kit and view de…
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Top Tips for Successful Development of Antibody Chromatography Processes
But working with protein L, that only binds kappa subclass one, three and four, for instance, MabSelect™ VL, you could get a really high purity sample during the capture step. Since the lambda heterod…