Search results for " throughput" in Articles / App Notes
Article
HTPD: Optimizing a mAb Chromatography Polishing Step
In this webinar, a case study using high throughput process development tools, optimizing process conditions for a mAb polishing step using a multimodal chromatography resin (Capto MMC ImpRes), will b…
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Single-use Bioreactors Have Reached the Big Time
Today there are systems available for high throughput R&D through to commercial production. Sartorius, for instance, through its acquisition of TAP Biosystems, now offers AMBR mini single-use bioreact…
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Reconciling Sensor Communication Gaps
Expression is “where the action is—where throughput and volumetric productivity exert the greatest influence on cost of goods.cleaning validation, and calibration.
The desirability of platform pur…
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Improving Process-Scale Chromatography
“Protein A enables a platform process for mAbs, thus enabling higher throughput of projects through process development and manufacturing,” she says.
Alternatives to Protein A chromatography are a…
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Walk Away and Do More Screening Preps
Learn how an ÄKTA pure protein purification system can be modified to increase throughput of mAb purifications and decrease hands-on time.
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Mixing dynamics in a large volume single use mixer
Large-volume mixers are mainly required in clinical three-scale and production-scale facilities where mixing efficiency is one of the key drivers of throughput efficiency. Upstream applications such …
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Process Chromatography Selection for Downstream Processing Applications
Protein A enables a platform process for mAbs thus enabling higher throughput of projects through process development and manufacturing.
BioPharm: What are some common chromatography column issues…
Article
Perfusion in the 21st Century
Currently, there is no perfusion device that can handle the working volumes typically used for high throughput techniques (1-200 mL). Industry efforts are underway to find alternative models that will…
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Fast Turnaround with Automated Column Packing
Packing success is, therefore, key to ensure an efficient purification process with high yield and throughput.
Packing success from the start
Today it is possible to get packing right on the f…
Article
Continuous Processing for the Production of Biopharmaceuticals
In addition to eliminating several hold steps, the advantages of this platform were realized in the form of increased process throughput and decreased equipment footprint.
Figure 2: Archi…