Search results for " throughput" in Articles / App Notes
Article
Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
The large number of samples produced challenges the throughput of existing analytical technologies. Assimilating all of the knowledge generated can be so overwhelming that the full benefit of the tech…
Article
Selecting the Right Viral Clearance Technology
By Cynthia Challener, PhD
The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug production that is well addressed by international regulatory requirements…
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A Q&A With Prof. Alois Jungbauer: The Role of HIC in Biotech
It is a good thing with the development of high throughput techniques and Design of Experiments. Otherwise, the multimodal chromatography approach would have been even more challenging. If we know the…
Article
Host-Cell Protein Measurement and Control
…e 1), remains as the industry gold standard for HCP measurement due to its high sensitivity and high throughput (3, 5). The HCP composition and abundance are unique to their respective host and the m…
Article
Ligand-Binding Assays and the Determination of Biosimilarity
Advances in SPR analysis have resulted in increased robustness of the assays and reduced operator influence, as well as increased throughput for the determination of binding affinities. Biolayer inter…
Article
Improving PAT for Biologics
High throughput methods
High-throughput process development systems and rapid analytical methods have the potential to reduce both the labor and time required to study both the many different vari…
Article
A Q&A With Dr. Anurag Rathore About the Future of QbD, Part I
Examples of such tools include high throughput process development, computational fluid dynamics, and use of advanced statistical approaches for designing experiments, analyzing data, and process cont…
Article
A Q&A With Phil Lester, co-organizer of the HTPD Conference
Can you tell us about the genesis of the conference?
Phil: Back in 2008 high throughput process development was an emerging technology and I could see it was going to be a game-changer. I thought …
Article
Analyzing Proteins Using SEC, MALS, and UHPLC
Greater throughput with smaller particle sizes
Several evolutionary advances in SEC have had a positive impact in recent years. Smaller flow cells and improved cell design, for example, have made …
Article
Challenges in Analytical Method Development and Validation
Depending on the intended use of the method, typical performance criteria (accuracy, reliability, specificity, sensitivity, range, robustness/maintenance, as well as speed and throughput capacity, but…