Search results for "bioprocess"
Article
Extractables Studies for Single Use Systems Used in ADC Manufacturing, Part 1
Single‑use (SU) systems have great potential in antibody‑drug conjugates (ADC) manufacturing. The use of organic solvents in the ADC process might , however, raise questions about potential leac…
Article
The Extreme Costs of a Bioburden Incident
The cost of bioburden incidents can vastly outweigh the costs of preventing them. Read the bioburden article series.
Article
Being Thorough When Transferring Technology
Communication and taking the time to develop the process are key to successful transfer and scale up of biologics.
By Susan Haigney
Editor's note: The following is an extended version of the…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
With the advent of quality by design, there have been renewed efforts toward gaining a deeper process understanding through mechanistic modeling of key bioprocess unit operations.
Researchers have…
Article
Ensuring the Biological Integrity of Raw Materials
Wisher, Bioprocess Int. 11 (9), pp. 12–15 (October 2013).
3. O.-W. Merten, Cytotechnol. 39, pp. 91–116 (2002).
4. J.G. Victoria et al., J. Virol. 84 (12), pp. 6033–6040 (June 2010).
Article
Evaluating E&L Studies for Single-Use Systems
Colton, Bioprocess Int. (supplement) 7(1), 88-94 (2009).
5. BPOG, Best Practices for Mitigating Risk from Leachables In Single-Use Systems, www.biophorum.com, available in January 2017.
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
In a bioprocessing setup, ReadyToProcess Adsorber membranes enable elimination of typical bottlenecks, such as facility fit, processing time, cleaning procedures, and overall changeover times.
At …
Article
Biosimilars to Drive Modern Manufacturing Approaches
“Advanced bioprocessing is beginning to take off,” she observed, acknowledging that innovator firms largely are taking the lead in this area. But she believes that the demand for affordable alternativ…
Poster
Improve operational efficiency in biomanufacturing with comprehensive automation solutions
However, equipment used are often connected only by process; that is, the bioprocess material passing between each of them. Often this connection is discontinuous, meaning equipment is controlled on a…
Article
Mixing dynamics in a large volume single use mixer
Large volume single-use technology mixers can be used for mixing operations throughout the entire bioprocess workflow. Large-volume mixers are mainly required in clinical three-scale and production…