Search results for "bioprocess"
Article
Perfusion in the 21st Century
Rader RA, Bioprocessing Journal 13 (1): 43-49 (2014).
7. D. Lyons et al., “Modeling Perfusion at Small Scale Using ambr15,” presented at Integrated Continuous Biomanufacturing II, San Francisco, C…
Article
Generating a Fully Processed Antibody
Bleck, Bioprocess J. 5, pp. 36–43 (2007).
About the Authors
Gregory Bleck is global head of R&D biologics; Dona York is director of upstream process development; and David Rabuka is global h…
Poster
Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression
This includes packing of traditional BioProcess™ media, such as the Sepharose™ family, in addition to the more modern high-flow agarose media, like Capto™ and MabSelect™ family. For most media the pac…
Article
Managing Biomanufacturing Capacity Expectations
The change can become more complicated if there is a change in product type, which may even require a completely different facility, says Tom Ransohoff, vice-president and principal consultant at BioP…
Article
An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
Testing product and process intermediates alone is helpful, but does not provide a complete solution to viral safety. This article proposes integrated solutions for systemic and proactive viral risk m…
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
Data acquired from osmolality, glucose, and folic acid tests provides useful information for the specific identification of cell-culture media.
By Satish Mallya, Benjamin Lay, Lihong McAleer, Alexa…
Article
Platform Approach Speeds Process Development
…omplex biopharmaceuticals such as recombinant monoclonal antibodies is dependent on high performing bioprocesses using mammalian host cells. Chinese hamster ovary (CHO)-based cell culture platforms s…
Article
Going Small to Achieve Success on the Commercial Scale
He adds that there is a lot of effort being devoted to overcoming these issues to enable high-throughput modeling of downstream bioprocesses.
A few groups are also investigating the application of…
Poster
Benchmarking, scalability, and protein production in CHO cell culture
The most widely used cell lines in the bioprocess industry originate from CHO cells. With the large number of CHO clones in use, it is important to have a cell culture medium that supports high via…
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics.
By Robert Karlsson
Abstract
Biotherapeutic antibodies are still the larg…