Search results for " market"
Article
Relationship Building at Top of Mind for Clients
The CMO market--particularly for non-commercial scale manufacture--is competitive. CMOs are juggling multiple projects at the same time, and when clients select the lowest bidder, it’s not hard to und…
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Single-Domain Antibodies for Brain Targeting
With 25 mAb products on the market and more than 100 undergoing clinical trials (1-3), it is evident that engineered antibodies have come of age as biopharmaceuticals (4).
Intact antibodies (immun…
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Global Expansion Shapes Drug Oversight
At the annual meeting of the Food and Drug Law Institute (FDLI) in April 2014, FDA commissioner Margaret Hamburg concluded her keynote address by describing a “dramatically changing global marketplace…
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Q&A with Industry Leaders: Rita Peters
Q: What trends have you seen in the drug development market as 2014 enters the second quarter?
A; At recent industry conferences and trade shows for pharmaceutical development, both educational se…
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Best Practices in Adopting Single-Use Systems
Proprietary components not generally available to the market at competitive prices will almost certainly add to cost and reduce customer choice. Bioprocessors can strengthen their long-term supply pos…
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Regulation of Biosimilars: A Matter of Variability, Similarity, and Comparability
The EU wants to keep ahead of the game in the regulation of biosimilars to give the region an advantage in establishing a large domestic market for the medicines. With the aim of helping to stimulate …
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Comparing Protein A Resins for Monoclonal Antibody Purification
Although it took some time for the first therapeutic mAb to become commercially available in 1986 (2), the market for therapeutic mAbs has since grown rapidly. MAbs have proved to be successful as tar…
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Evolution of the Monoclonal Antibody Purification Platform
Use of multimodal chromatography
Recently, mixed-mode, ion-exchange ligands with enhanced binding strength for aggregates through the addition of hydrophobic functionality have been brought to mar…
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Biosimilars Development and Supply: How Complex Can the Process Be?
The goals behind the safe and regulated introduction of biosimilars into the market include increasing access to much-needed biologic medicines and reducing costs (2).
A recent report (3) from …
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HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
ABSTRACT
Monoclonal antibodies represent a significant portion of sales in the biopharmaceuticals market. Ever-growing biotechnology pipelines have greatly increased demand for higher throughput, …