Search results for " preparative" in Articles / App Notes
Article
Make buffer preparation more time and cost efficient with inline conditioning
Simplify Buffer Preparation
The volume and number of buffers for a typical downstream process can be considerable.
Preparation of these buffers is a challenge that in-line conditioning can o…
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Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
Buffer preparation requires extensive footprint and is also resource intensive. In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large…
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Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-li…
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Can You Trust a Machine for Downstream Bioprocess Buffer Preparation?
There is a limit to how many stainless-steel tanks you can squeeze into a biomanufacturing facility. Still, resource-intensive buffer preparation has received little attention in biomanufacturing. S…
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Tutorial: Automated Preparation of Buffer Plates
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Preparing buffers manually for buffer conditions screening might be very time consuming. This video shows how to use the BufferPro function in ÄKTA avant for automated …
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Discover new ways to improve buffer preparation
Large quantities of buffers are needed throughout the biomanufacturing process. Most biomanufacturers are still preparing their buffers manually, tying up significant resources, but there are b…
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Prepare for an FDA Bioburden Inspection
Even with effective prevention, bioburden incidents can occur. A best-practices response will not only help you be prepared for any upcoming FDA inspection, it may also yield valuable insights to help…
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Mechanistic Modeling of Preparative Ion-Exchange Chromatography
Seidel-Morgenstern, “Modeling and Model Parameters,” in Preparative Chromatography, (Wiley-VCH verlag GmbH & Co. KgaA, 2nd ed., 2012), pp. 321–424.
3. V. Kumar et al., J. Chromatogr. A 1426, 1…
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Automated Buffer Preparation with Inline Conditioning Technology
Inline conditioning (IC) technology allows for buffers to be produced from single-component stock concentrates when needed, at the point-of-use (POU). IC automates buffer production, s…
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Preparing for the Future Visions and Insights for Biomanufacturing
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The biopharmaceutical industry has a reputation of being averse to change. Yet, new market dynamics, such as growing competition from biosimilars and niche drugs targe…