Search results for " preparative"
Article
Make buffer preparation more time and cost efficient with inline conditioning
Simplify Buffer Preparation
The volume and number of buffers for a typical downstream process can be considerable.
Preparation of these buffers is a challenge that in-line conditioning can o…
Article
Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
Buffer preparation requires extensive footprint and is also resource intensive. In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large…
Article
Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-li…
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Can You Trust a Machine for Downstream Bioprocess Buffer Preparation?
There is a limit to how many stainless-steel tanks you can squeeze into a biomanufacturing facility. Still, resource-intensive buffer preparation has received little attention in biomanufacturing. S…
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Tutorial: Automated Preparation of Buffer Plates
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Preparing buffers manually for buffer conditions screening might be very time consuming. This video shows how to use the BufferPro function in ÄKTA avant for automated …
Poster
Scaling In-Line Buffer Preparation from Process Development to Manufacturing
Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is one possible way to address these challenges. At the same t…
Article
Discover new ways to improve buffer preparation
Large quantities of buffers are needed throughout the biomanufacturing process. Most biomanufacturers are still preparing their buffers manually, tying up significant resources, but there are b…
Article
Prepare for an FDA Bioburden Inspection
Even with effective prevention, bioburden incidents can occur. A best-practices response will not only help you be prepared for any upcoming FDA inspection, it may also yield valuable insights to help…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
Seidel-Morgenstern, “Modeling and Model Parameters,” in Preparative Chromatography, (Wiley-VCH verlag GmbH & Co. KgaA, 2nd ed., 2012), pp. 321–424.
3. V. Kumar et al., J. Chromatogr. A 1426, 1…
Article
Automated Buffer Preparation with Inline Conditioning Technology
Inline conditioning (IC) technology allows for buffers to be produced from single-component stock concentrates when needed, at the point-of-use (POU). IC automates buffer production, s…