Search results for " process" in Articles / App Notes
Article
Genetic Vaccine Platforms Demonstrate Their Potential
“The process to develop and produce genetic vaccines is highly similar from one to the next, so we have already a lot of information from other vaccine projects that have used the same platform. This …
Article
Gene Therapies Push Viral Vector Production
“The process of changing the tropism of the vectors is referred to as pseudotyping. For instance, Agilent has retroviral and lentiviral vector systems that are pseudotyped to achieve a wide target ran…
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Essentials in Quality Risk Management
…manufacturing and changes in drug-product formulation, definition, analytical method, and associated process changes are understood and managed to ensure patient safety and drug efficacy. An effectiv…
Article
Automating Bioprocesses
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used stainless-steel equipment, but use of single-use systems (SUS) is becoming more established.…
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Challenges and Trends in Biopharma Facility Design
High-yield processes, single-use equipment, and modular concepts are tools contributing to the ability to meet the demands of these new facilities.
Kranjac (Cytiva): As bioprocess infrastructure t…
Article
Reimagining Affordable Biosimilars
Limitations of clinical studies
Clinical trials have long served as the gold standard for evaluating safety and efficacy of drugs in a systematic manner using established, robust statistical pro…
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Modeling and Miniaturization: Key Topics at Successful HTPD Conference
The HTPD conference series started as a joint initiative by Cytiva and Genentech in 2010 at a time when high-throughput process development (HTPD) was in its early days. HTPD was mainly limited to 96-…
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
… ensure they fully realize the benefits?
Facility design is a complex, multi-faceted, multi-step process, and early decisions can cause unforeseen limitations as the project progresses or, later,…
Article
Lessons Learned Accelerate Vaccine Development
Challener
Vaccine development is a complicated process that can take many years to bear fruit. More complicated diseases such as AIDS and malaria have proven particularly challenging in this respe…
Article
Evolution of the Monoclonal Antibody Purification Platform
What is unique about mAbs from a processing perspective is the applicability of developing a common process and analytical platform (2, 3). Some process development related attributes with respect to …