Search results for " analytics"

Article The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges. By Kelvin H. Lee and Mark Lies …

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
Process analytics for purification of monoclonal antibodies. J Chromatogr B. 2007;848:79–87. 16. Farnan D, Moreno GT. Multi-product high-resolution monoclonal antibody charge variant separations b…

Article PDA's Technical Report for Biotech Cleaning Validation
The authors encourage biotech manufacturers to consult PDA Technical Report No. 49 for a detailed perspective on current practices and issues in biotech cleaning validation. By Anurag S. Rathore, D…

Article Impurity Testing of Biologic Drug Products
Experts share insights on the various methods used for purity and impurity analysis of therapeutic proteins. By Adeline Siew, PhD  CA-SSIS/shutterstock.comIm…

Article Evaluating Surface Cleanliness Using a Risk-Based Approach
Evaluating Surface Cleanliness Using a Risk-Based Approach Rinse sample analysis or visual inspection can be correlated to surface cleanliness to replace surface sampling. By Elizabeth Rivera…

Article Reviewing the Importance of Biosimilarity and Interchangeability
Developing a robust and reliable strategy for analytical studies of a biosimilar in development is crucial for a successful regulatory pathway. The importance of biosimilar products is tied to…

Article Nurturing Knowledge from Disparate Data Streams
Leveraging vast quantities of analytical data requires digitalization and platform integration. By Cynthia A. Challener jijomathai/stock.Adobe.comAnalytical instrument…

Article Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Summary Analytical exoglycosidases are transitioning from being largely academic tools to being suitable for glycan analytics in industries where consistency and accuracy are of paramount importan…

Article Reimagining Affordable Biosimilars
With use of “omics” tools, big-data analytics, bio-mathematical modeling, and in-silico and in-vitro tools, there can be a transformation in the preclinical development of biosimilars. Reference…

Article Moving PAT from Concept to Reality
Hence, these processes benefit from a stricter control strategy, where high levels of automation and implementation of PAT and advanced data analytics play a key role,” Grieb asserts. Essential fo…

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