Search results for " medium" in Posters
Poster
Development of a chemically defined medium for virus vaccine production in a duck suspension cell line
The primary goal of this project was to develop a chemically defined medium that could be used in a monophasic process while supporting the growth and production of a broad spectrum of different virus…
Poster
Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplement…
Poster
Optimizing productivity on high capacity protein A affinity medium
MabSelect SuRe™ protein A affinity medium has long been considered a starndard tool for capturing monoclonal antibodies in biopharmaceutical production. This application note summarizes studies on d…
Poster
Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression
Axial compression allows for optimally packed beds also in the large-scale chromatography column range. Different methods have been developed to pack a broad range of chromatography media (resins) i…
Poster
Benchmarking, scalability, and protein production in CHO cell culture
With the large number of CHO clones in use, it is important to have a cell culture medium that supports high viable cell counts and productivity with multiple cell clones. A precise balance of nutri…
Poster
Purification platform challenges and strategies for handling of "tricky" MAbs
In the work presented here, capture using high-capacity protein A medium (resin) was followed by polishing using a novel cation exchange chromatography medium.
Poster
Effects of feeding strategy on CHO cell performance in fed-batch cultures
ActiPro cell culture production medium is intended to be used in combination with Cell Boost 7a and 7b supplements to enhance recombinant protein production in fed-batch or perfusion processes. This…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
Here, we describe different approaches for the cultivation of Vero cells using Cytodex and Cytodex Gamma microcarriers in serum-free cultivation medium using spinners, WAVE Bioreactor™ 20/50, ReadyToP…
Poster
Modes of controlling charge variant distribution in Mab production
In this study, we investigated the effects of cell culture process parameters and medium components on charge variant distribution of a human IgG1 MAb. Furthermore, the MAb charge variant clearance in…
Poster
Optimizing dynamic binding capacity and aggregate clearance in an mAb polishing step
Capto™ S ImpAct is a strong cation exchange (CIEX) chromatography medium (resin) designed for monoclonal antibody (MAb) polishing steps. In this study, optimization of binding conditions targeting h…