Search results for " throughput"
Article
Process Chromatography Selection for Downstream Processing Applications
Protein A enables a platform process for mAbs thus enabling higher throughput of projects through process development and manufacturing.
BioPharm: What are some common chromatography column issues…
Article
Perfusion in the 21st Century
Currently, there is no perfusion device that can handle the working volumes typically used for high throughput techniques (1-200 mL). Industry efforts are underway to find alternative models that will…
Poster
Residual DNA analysis in influenza vaccine processing
In cell-based influenza vaccine production, the European Pharmacopoeia demands a host cell residual DNA concentration of less than 10 ng per dose. To reliably measure residual DNA in both process sa…
Article
Fast Turnaround with Automated Column Packing
Packing success is, therefore, key to ensure an efficient purification process with high yield and throughput.
Packing success from the start
Today it is possible to get packing right on the f…
Poster
Integration of continuous upstream and downstream operations in mAb production
Process intensification is gaining interest as a strategy to reduce production costs, while improving product quality and throughput in the manufacturing of biopharmaceuticals. For a competitive pro…
Article
Continuous Processing for the Production of Biopharmaceuticals
In addition to eliminating several hold steps, the advantages of this platform were realized in the form of increased process throughput and decreased equipment footprint.
Figure 2: Archi…
Article
Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
The large number of samples produced challenges the throughput of existing analytical technologies. Assimilating all of the knowledge generated can be so overwhelming that the full benefit of the tech…
Article
Selecting the Right Viral Clearance Technology
By Cynthia Challener, PhD
The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug production that is well addressed by international regulatory requirements…
Poster
Process economy and production capacity using single-use versus stainless steel fermentation equipment
The increased batch throughput also generates a greater profit opportunity, which benefits can outnumber the higher production cost per batch associated with the single-use alternative. With the decre…
Article
A Q&A With Prof. Alois Jungbauer: The Role of HIC in Biotech
It is a good thing with the development of high throughput techniques and Design of Experiments. Otherwise, the multimodal chromatography approach would have been even more challenging. If we know the…