Search results for " concentration"
Article
Continuous Chromatography: Trends, Definitions and Approaches
For the very low titer processes, or rather for the cases where the ratio of capacity-to-feed concentration is very high, even a 2-column system will be sufficient.
Can you comment on the import…
Article
Re-use of Protein A Resin: Fouling and Economics
Other significant attributes include the level of Protein A leachate in the pool, concentration of DNA in the pool, growth media composition, and the amount of lipids in the pool (Figure 4A).
Figu…
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Trends in Single-use Bioreactors
Representatives from industry supplier companies address innovations, reliability, barriers to adoption, and the role of singIe-use bioreactors in bioprocessing.
By: Randi Hernandez
Whil…
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Evaluating Design Margin, Edge of Failure and Process
When the edge of failure analysis is generated, however, there is a high failure rate for concentration. Examination of the edge of failure makes sure the set point is safe in the design space and the…
Article
Single-Domain Antibodies for Brain Targeting
sdAbs have similar affinity to antigens as whole antibodies, but are more heat-resistant and stable towards detergents and high urea concentrations. Those derived from camelid and fish antibodies are …
Article
Outsourcing Trends in Biopharmaceutical Manufacturing
The author highlights the top 10 outsourcing trends revealed during a survey of biopharmaceutical manufacturers.
The biopharmaceutical industry is changing the way it manufactures. According to …
Article
Biotechnology Innovation and Growth in Israel
Israel's diverse population, high-quality healthcare system, and resilience to global financial stress make it a strong partner for R&D, clinical research, and market growth.
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Article
Essentials in Establishing and Using Design Space
Design space is the result of system design, the selection of all reagents, excipients, API concentrations, materials, equipment, process set points, and tolerances.
Methods for Design-Space …
Article
Milestones and Moderate Progress in 2012 Drug Approvals
It is approved for treatment of toxic plasma methotrexate concentrations in patients with delayed methotrexate clearance due to impaired renal function. Methotrexate is an anti-folate antimetabolite w…
Article
Quality by design for biotechnology products—part 1
For the reactor expansion unit operation, for example, the cell growth, viable cell density, culture viability, and glucose concentration may be affected by the inoculum, medium, bioreactor operation,…