Search results for "chromatography"
Article
Methods Accelerate Biosimilar Analysis
For more detailed and accurate quantification of these modifications and to identify the sites where these modifications occur, however, it is necessary to perform peptide mapping by liquid chromatogr…
Article
Emerging Therapies Test Existing Bioanalytical Methods
… in vivo?
The assays used to measure these characteristics are often not traditional liquid chromatography–mass spectrometry (LC–MS) or ELISA used to quantify small- and large-molecule therap…
Poster
Scaling In-Line Buffer Preparation from Process Development to Manufacturing
Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is one possible way to address these challenges. At the same t…
Article
Case Study: Virus Reduction of an Affinity Capture Step
Evaluating how much a process step contributes to viral clearance is an essential part of process validation. For this reason, there is an industry need to perform effective viral clearance studies. I…
Article
New HiScale™ 10/40 for Scale-Down Studies
Cytiva is pleased to announced the new HiScale™ 10/40.
HiScale 10/40 column is especially suitable for scale-down studies used in, for example, viral clearance evaluation in downstream processing. …
Article
New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from Cytiva.
Download the Packing Guide
Article
New Column for Scale-Down Studies
Cytiva is pleased to announce new Validation columns.
Their dimensions—narrow 10 mm inner diameter, combined with 20 cm bed height typically used in biomanufacturing—make these columns suitable …
Article
Experience Compact Scalability
Cost and speed are critical components in biomanufacturing. Can you get a good balance between these two things for your purification tasks, whether you are developing a process or manufacturing at pi…
Article
An Analytical Approach to Biosimilar Drug Development
As a result, demand has increased for chromatography and mass spectrometry technology providers to design instrumentation, software informatics, and workflows to support protein analysis studies. In a…
Poster
To Speed Up the Process Optimization of the Described Biosimilar Product
This example describes a standardized workflow using a highthroughput process development (HTPD) approach: chromatography resin and running conditions were selected based on experience and adapted to …