Search results for " downstream"
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Dear lentivirus: We have not forgotten about you and how to improve your polishing recovery
To maximize physical and infectious titer, it’s important to carefully tune the conditions of each downstream step with these sensitivities in mind.
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Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient downstream proce…
Article
Optimization of a two-step purification method for bispecific antibodies
This presentation shows the results from Cytiva collaborating with Alligator to develop an efficient downstream purification process for a cancer immunotherapy bispecific antibody (bsAb). A two-step p…
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Free eBook: Considerations for smarter and faster process development
What you will learn:
Industry drivers to go smarter and faster in process development
Strategies for more efficient upstream process development
Strategies for more efficient down…
Article
Implementing Inline Conditioning to Advance Process Intensification
…ne of the biggest challenges was accommodating over 170,000 liters of buffers that is needed for the downstream processing of one batch. IC technology is based on the use of concentrated stock soluti…
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Successful Development of Scalable AAV Processes: Part 2 of 2
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In the second of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist, Bio…
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Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Watch the Q&A interview >>
In the first of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
By producing less waste upstream, there is the potential benefit of having less burden downstream in the separation and purification steps. However, the practicality of using cell-free expression syst…
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Virus-like Particles as Therapeutic Moieties of the Future
Modification of VLPs may also affect their downstream application. Identification of the composition is thus a prerequisite for characterization of VLPs.
Mass spectrometry (MS) is a robust tool to…
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Reimagining Affordable Biosimilars
Near-infrared spectroscopic methods find application as process analytical tools in upstream and downstream processing of biotherapeutics, aiding in process control. Unique spectral signature of chemi…