Search results for " titers" in Articles / App Notes
Article
Dear lentivirus: We have not forgotten about you and how to improve your polishing recovery
Lentiviruses are commonly used for both chimeric antigen receptor (CAR) T cell therapy and ex vivo gene therapy.
Vector purification is very challenging due to low stability of these envel…
Article
Enhancing Resins Addresses Purification Concerns
“As upstream processing continues to increase titers of these biologic molecules, improving on current chromatography resins to increase the dynamic binding capacity while enhancing separation to remo…
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Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
Article
Setting Up Bioprocessing Systems for Digital Transformation
Digitalization of bioprocessing operations, equipment, and facilities can improve workflow and output, but maintaining data integrity is a concern.
By Feliza Mirasol
The advancement of digit…
Article
Process Development: Go Smarter, Go Faster! Available on Demand
…ment with the latest techniques and ways of working
• Enhance outcomes: Increase titers and yields while ensuring robust processes
• Overcome obstacles: Address the challenges generated …
Article
HyClone Characterized FBS – Origin Equivalence Study
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Fetal bovine serum (FBS) is still used in many cell culture applications, including viral vector production. FBS from a single origin may be limited, so qualifying FBS from …
Article
DiPIA online
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Biacore surface plasmon resonance application specialists are eager to share their experience in assay design, validation, and data evaluation.
Article
Considerations for Improving Outcome in Biopharmaceutical Process Development
For example, things like streamlining operations, optimizing titers and yields, evaluating cell lines and cell culture media, and controlling raw material variability can play a pivotal role in obtain…
Article
Towards a Better Process Outcome
Considerations for improving outcome in biopharmaceutical process development.
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Article
Flavivirus Vaccine: Accelerate Development and Production with Modern Tools and Solutions
The complex nature of flaviviruses makes process development technically challenging. In addition, vaccine production can be both costly and difficult to scale to meet market demands. This article giv…